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1

Scintillation Proximity Assays in High-Throughput Screening

Glickman, J. Fraser, Schmid, Andres, Ferrand, Sandrine

Journal:

Assay and Drug Development Technologies

Year:

2008

Language:

english

File:

PDF, 32.10 MB

english, 2008

2

Special ergolines are highly selective, potent antagonists of the chemokine receptor CXCR3: Discovery, characterization and preliminary SAR of a promising lead

Gebhard Thoma, Rolf Baenteli, Ian Lewis, Trixie Wagner, Lukas Oberer, Wolfgang Blum, Fraser Glickman, Markus B. Streiff, Hans-Guenter Zerwes

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 372 KB

english, 2009

3

An imaging assay to analyze primary neurons for cellular neurotoxicity

Marjo Götte, Gabriele Hofmann, Anne-Isabelle Michou-Gallani, J. Fraser Glickman, William Wishart, Daniela Gabriel

Journal:

Journal of Neuroscience Methods

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

4

Optimizing screening technology: how much to invest?

J.Fraser Glickman

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 37 KB

english, 2001

5

Optimizing screening technology: how much to invest? – Reply

J.Fraser Glickman

Journal:

Drug Discovery Today

Year:

2001

Language:

english

File:

PDF, 64 KB

english, 2001

6

The antiproliferative effects of staurosporine are not exclusively mediated by inhibition of protein kinase C

Charles D. Smith, J. Fraser Glickman, Kwen-Jen Chang

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 350 KB

english, 1988

7

Purification and Characterization of Recombinant Baculovirus-Expressed Mouse DNA Methyltransferase

J.Fraser Glickman, James Flynn, Norbert O. Reich

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 229 KB

english, 1997

8

Orally Bioavailable Isothioureas Block Function of the Chemokine Receptor CXCR4 In Vitro and In Vivo

Thoma, Gebhard, Streiff, Markus B., Kovarik, Jiri, Glickman, Fraser, Wagner, Trixie, Beerli, Christian, Zerwes, Hans-Günter

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 193 KB

english, 2008

9

Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling

Petrova, Elissaveta, Rios-Esteves, Jessica, Ouerfelli, Ouathek, Glickman, J Fraser, Resh, Marilyn D

Journal:

Nature Chemical Biology

Year:

2013

Language:

english

File:

PDF, 650 KB

english, 2013

10

Ligand-Receptor Binding Measured by Laser-Scanning Imaging

Paul Zuck, Zhege Lao, Stephen Skwish, J. Fraser Glickman, Ke Yang, Jonathan Burbaum and James Inglese

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.42 MB

english, 1999

11

Murine DNA Cytosine-C 5 Methyltransferase: Pre-Steady- and Steady-State Kinetic Analysis with Regulatory DNA Sequences †

Flynn, James, Glickman, J. Fraser, Reich, Norbert O.

Journal:

Year:

1996

Language:

english

File:

PDF, 553 KB

english, 1996

12

A Difficult Host for Malaria Cells

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 124 KB

english, 2004

13

Re- μ arcs on a New Kinase Assay Format

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 69 KB

english, 2004

14

Farnesyl Pyrophosphate Synthase: Real-Time Kinetics and Inhibition by Nitrogen-Containing Bisphosphonates in a Scintillation Assay

Glickman, J. Fraser, Schmid, Andres

Journal:

Assay and Drug Development Technologies

Year:

2007

Language:

english

File:

PDF, 454 KB

english, 2007

15

Literature Search and Review

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

16

Literature Search and Reviews

Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 435 KB

english, 2003

17

Binding: Going Through a Phase

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 53 KB

english, 2004

18

The Proteomics of Kinase Selectivity

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 113 KB

english, 2004

19

Literature Search and Review

Fraser Glickman, J., Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

20

Controversies in ASSAY and Drug Development Technologies : A Focus on Assessing Irreproducibility

Glickman, J. Fraser, Lundbäck, Thomas, Napper, Andrew D., Niles, Walter D., Simeonov, Anton, Weaver, C. David, Yin, Hongwei Holly, Zaman, Guido J.R., Osada, Hiroyuki

Journal:

Assay and Drug Development Technologies

Year:

2014

Language:

english

File:

PDF, 226 KB

english, 2014

21

Literature Search and Review

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2005

Language:

english

File:

PDF, 367 KB

english, 2005

22

Have You Heard the Latest "Drug" CD?

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 69 KB

english, 2004

23

Literature Search and Reviews

Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 253 KB

english, 2003

24

Literature Search and Reviews

Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 135 KB

english, 2003

25

More Metallic Assays

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

26

Literature Search and Review

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 760 KB

english, 2004

27

Characterization of Fatty Acid Synthase Activity Using Scintillation Proximity

Weiss, Donna R., Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 178 KB

english, 2003

28

Inflammatory Statements

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 47 KB

english, 2004

29

More Kinase Assays

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

30

High Content Binding

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 58 KB

english, 2004

31

Literature Search and Review

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

32

Statistical Evaluation of a Self-Deconvoluting Matrix Strategy for High-Throughput Screening of the CXCR3 Receptor

Ferrand, Sandrine, Schmid, Andres, Engeloch, Caroline, Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2005

Language:

english

File:

PDF, 438 KB

english, 2005

33

Literature Search and Review

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

34

Literature Search and Reviews

Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

35

Literature Search and Reviews

Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 500 KB

english, 2003

36

Literature Search and Review

Glickman, J. Fraser

Journal:

Assay and Drug Development Technologies

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

37

Put a Leash on Your Cells

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 143 KB

english, 2004

38

IP 3 in '03

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 66 KB

english, 2004

39

Literature Search and Review

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2005

Language:

english

File:

PDF, 628 KB

english, 2005

40

A Biological Role for Prions

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

41

Speedy Screens Done Dirt Cheap

Glickman, J. Fraser, Auld, Doug

Journal:

Assay and Drug Development Technologies

Year:

2004

Language:

english

File:

PDF, 106 KB

english, 2004

42

Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers

Chandramouly, Gurushankar, McDevitt, Shane, Sullivan, Katherine, Kent, Tatiana, Luz, Antonio, Glickman, J. Fraser, Andrake, Mark, Skorski, Tomasz, Pomerantz, Richard T.

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 2.96 MB

english, 2015

43

Alzheimer's disease peptide β-amyloid interacts with fibrinogen and induces its oligomerization

Hyung Jin Ahn, Daria Zamolodchikov, Marta Cortes-Canteli, Erin H. Norris, J. Fraser Glickman, Sidney Strickland and Anthony Cerami

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

44

A Comparison of ALPHAScreen, TR-FRET, and TRF as Assay Methods for FXR Nuclear Receptors

Glickman, J. Fraser, Wu, Xiang, Mercuri, Robert, Illy, Chantal, Bowen, Benjamin R., He, Yang, Sills, Matthew

Journal:

Journal of Biomolecular Screening

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

45

Bithionol potently inhibits human soluble adenylyl cyclase through binding to the allosteric activator site

Kleinboelting, Silke, Ramos-Espiritu, Lavoisier, Buck, Hannes, Colis, Laureen, van den Heuvel, Joop, Glickman, J. Fraser, Levin, Lonny R., Buck, Jochen, Steegborn, Clemens

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 925 KB

english, 2016

46

Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates

Sandu, Cristinel, Chandramouli, Nagaranjan, Glickman, Joseph Fraser, Molina, Henrik, Kuo, Chueh-Ling, Kukushkin, Nikolay, Goldberg, Alfred L., Steller, Hermann

Journal:

Journal of Cellular and Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 2.06 MB

english, 2015

47

Predicting Drug Toxicity: Early Detection of Likely Failures in Drug Development

Sanford, R. Lea, Chao, Wesley, Chiaravalli-Giganti, Jeanne, Luz, Antonio, Glickman, J. Fraser, Andersen, Olaf S.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

48

Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding

Marzinzik, Andreas L., Amstutz, René, Bold, Guido, Bourgier, Emmanuelle, Cotesta, Simona, Glickman, J. Fraser, Götte, Marjo, Henry, Christelle, Lehmann, Sylvie, Hartwieg, J. Constanze D., Ofner, Silvi

Journal:

Year:

2015

Language:

english

File:

PDF, 2.03 MB

english, 2015

49

The Antibiotic Azatyrosine Suppresses Progesterone or [Val12]p21 Ha-ras/Insulin-like Growth Factor I-Induced Germinal Vesicle Breakdown and Tyrosine Phosphorylation of Xenopus Mitogen-Activated Protein Kinase in Oocytes

Michael J. Campa, J. Fraser Glickman, Kyohei Yamamoto and Kwen-Jen Chang

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.22 MB

english, 1992

50

Membranes Matter: Predicting Drug Toxicity

Lea Sanford, R., Chao, Wesley, Chiaravalli-Giganti, Jeanne, Luz, Antonio, Glickman, J. Fraser, Andersen, Olaf S.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 42 KB

english, 2017